Synthesis of betaines from 1,4-diaza[2.2.2]bicyclooctane

Authors

  • А. O. Казанцев Dzerzhinsk Branch, Novgorod State Medical University, Dzerzhinsk 606007
  • С. A. Казаков Dzerzhinsk Branch, Novgorod State Medical University, Dzerzhinsk 606007
  • K. B. Ширшин Dzerzhinsk Branch, Novgorod State Medical University, Dzerzhinsk 606007
  • C. М. Данов Dzerzhinsk Branch, Novgorod State Medical University, Dzerzhinsk 606007
  • В. Л. Краснов Dzerzhinsk Branch, Novgorod State Medical University, Dzerzhinsk 606007

Abstract

Betaine formation occurs on reacting 1,4-diaza[2.2.2]bicyclooctane with acrylic acid, 2-acrylamido-2-methylpropanesulfonic acid, and 4-acrylamido-4-methyltetrahydrothiophene-1,1-dioxide-3-sulfonic acid. Various products such as monobetaines, their salts, or dibetaines may be obtained in the reaction with acrylic acid depending on the solvent and the reactant ratio. With an excess of diamine reaction occurs more rapidly with sulfonic acids, but with a deficiency of diamine reaction occurs more rapidly with the carboxylic acid.

How to Cite
Kazantsev, A. O.; Kazakov, S. A.; Shirshin, K. V.; Danov, S. M.; Krasnov, V. L. Chem. Heterocycl. Compd. 1998, 34, 484. [Khim. Geterotsikl. Soedin. 1998, 34, 547.]

For this article in the English edition, see DOI https://doi.org/10.1007/BF02290891

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Published

1998-04-25

Issue

No. 4 (1998)

Section

Original Papers