Synthesis and alkylation of pyridylacetylenes under phase transfer catalysis conditions in a liquid/solid system

Authors

  • Э. Абелe Latvian Institute of Organic Synthesis, Riga LV-1006
  • P. Абеле Latvian Institute of Organic Synthesis, Riga LV-1006
  • К. Рубина Latvian Institute of Organic Synthesis, Riga LV-1006
  • А. Гаухман Latvian Institute of Organic Synthesis, Riga LV-1006
  • Э. Лукевиц Latvian Institute of Organic Synthesis, Riga LV-1006

Abstract

We have investigated the alkylation of 2-methyl-5-ethynylpyridine by butyl bromide in liquid/liquid and liquid/solid two-phase catalytic systems. We have shown that the catalytic system solid KOH/18-crown-6/CuBr/toluene is the most active in this reaction; using this system, we obtained alkylation products of ethynylpyridines in 34–43% yields.

How to Cite
Abele, É.; Abele, R.; Rubina, K.; Gaukhman, A.Lukevics, E. Chem. Heterocycl. Compd. 1998, 34, 459. [Khim. Geterotsikl. Soedin. 1998, 34, 518.]

For this article in the English edition, see DOI https://doi.org/10.1007/BF02290886

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Published

1998-04-25

Issue

No. 4 (1998)

Section

Original Papers