Synthesis and properties of esters of benzothiazolylamino(imino)propionic acids

Abstract

Reaction of 2-alkylaminothiazoles with methyl acrylate leads predominantly to the formation of N-alkyl-N-(β-methoxycarbonylethyl)-2-aminobenzothiazoles on boiling or to 2-(alkylimino)-3-(β-methoxycarbonylethyl)-benzothiazolines at room temperature. A complex mixture of products was obtained from unsubstituted 2-aminobenzothiazole and methyl acrylate, of which the main was 2-oxo-3,4-dihydro-2H-pyrimido[2,1-b]benzothiazole. Complete or partial destruction of the benzothiazolines occurred on heating to 140°C.

How to Cite
Ambartsumova, R. F. Chem. Heterocycl. Compd. 1997, 33, 859 [Khim. Geterotsikl. Soedin. 1997, 981.]

For this article in the English edition, see DOI https://doi.org/10.1007/BF02253042