Synthesis of 5-substituted 2-nitraminopyrimidines and 2-hydroxyaminopyrimidines

Authors

  • Г. Г. Москаленко Novosibirsk Institute of Organic Chemistry, Siberian Branch of the Russian Academy of Sciences, Novosibirsk 630090
  • O. П. Шкурко Novosibirsk Institute of Organic Chemistry

Abstract

2-Nitraminopyrimidine and its 5-R derivatives (R=Me, Cl, NO2, Ph, p-O2NC6H4) have been prepared by cyclization of nitroguanidine with 2-methyl-3-dimethylaminoacrolein or bis(dimethylamino)trimethinium salts, and also by nitration of the corresponding aminopyrimidines. By interaction of these nitramino derivatives with hydroxylamine, substituted 2-hydroxyaminopyrimidines have been obtained.

How to Cite
Moskalenko, G. G.; Shkurko, O. P. Chem. Heterocycl. Compd. 1997, 33, 1. [Khim. Geterotsikl. Soedin. 1997, 1.]

For this article in the English edition, see DOI https://doi.org/10.1007/BF02253037

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Published

1997-07-25

Issue

No. 7 (1997)

Section

Original Papers