Shapiro reaction in the series of piperidine derivatives. Synthesis of 3-hydroxy-1,2,3,6-tetrahydropyridines

Abstract

It is shown that the reaction of tosylhydrazones of 3-hydroxypiperidin-4-ones with bases, depending on the nature of the latter, results in a rearrangement with a narrowing of the heterocycle and formation of acetylpyrrolidines, or in the formation of 3-hydroxy-1,2,3,6-tetrahydropyridines.

How to Cite
Zvonok, A. M.; Okaev, E. B. Chem. Heterocycl. Compd. 1996, 32, 310. [Khim. Geterotsikl. Soedin. 1996, 361.]

For this article in the English edition, see DOI https://doi.org/10.1007/BF01169248