4-hydroxy-2-quinolones. 24. Improved synthesis and biological properties of hydrochlorides of β-dialkylaminoalkylamides of 1-alkyl-2-oxo-4-hydroxyquinoline-3-carboxylic acids

Authors

  • И. B. Украинец Ukrainian Pharmaceutical Academy, Kharkov 310002
  • O. B. Горохова Ukrainian Pharmaceutical Academy, Kharkov 310002
  • С. Г. Таран Ukrainian Pharmaceutical Academy, Kharkov 310002
  • П. А. Безуглый Ukrainian Pharmaceutical Academy, Kharkov 310002
  • Н. И. Филимоновa Ukrainian Pharmaceutical Academy, Kharkov 310002
  • А. В. Туров Ukrainian Pharmaceutical Academy, Kharkov 310002

Abstract

High-purity hydrochlorides of β-dialkylaminoalkylamides of 1-R-2-oxo-4-hydroxyquinoline-3-carboxylic acids have been obtained from N-alkyl-2-carbalkoxyanilides of malonic acid. The synthesized compounds have been tested for certain forms of pharmacological activity.

How to Cite
Ukrainets, I. V.; Gorokhova, O. V.; Taran, S. G.; Bezuglyi, P. A.; Filimonova, N. I.; Turov, A. V. Chem. Heterocycl. Compd. 1994, 30, 1214. [Khim. Geterotsikl. Soedin. 1994, 1400.]

For this article in the English edition, see DOI https://doi.org/10.1007/BF01184888

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Published

1994-10-25

Issue

No. 10 (1994)

Section

Original Papers