SYNTHESIS OF 3-SUBSTITUTED 2-AMINO-1-HYDROXY-1<i>H</i>-INDOLE-5,6-DICARBONITRILES
DOI:
https://doi.org/10.1007/1231Keywords:
2, 1-benzisoxazoles, 1-hydroxy-1H-indole-5, 6-dicarbonitriles, phthalonitriles, C-nucleophilic substitution, reductive cyclizationAbstract
A method of synthesizing new 3-substituted 2-amino-1-hydroxy-1H-indole-5,6-dicarbonitriles has been developed based on the reductive cyclization of substituted 4-cyanomethyl-5-nitrophthalonitriles.
Authors: S. I. Filimonov, Zh. V. Chirkova, V. S. Sharunov, I. G. Abramov, G. A. Stashina, S. I. Firgang, and K. Yu. Suponitsky.
English Translation in Chemistry of Heterocyclic Compounds, 2012, 48 (3), pp 427-435