SYNTHESIS OF 2-SUBSTITUTED (2<i>R</i>,4<i>R</i>)-3-(3-MERCAPTOPROPIONYL)THIAZOLIDINE-4-CARBOXYLIC ACIDS

Authors

  • A. Ю. Ершов Institute of Macromolecular Compounds, Russian Academy of Sciences
  • Д. Г. Наследов Institute of Macromolecular Compounds, Russian Academy of Sciences
  • И. В. Лагода Scientific Research and Testing Center for Biomedical Defense, State Scientific Research and Testing Institute of Military Medicine, Ministry of Defense of the Russian Federation
  • В. В. Шаманин Institute of Macromolecular Compounds, Russian Academy of Sciences

DOI:

https://doi.org/10.1007/1802

Keywords:

aldehydes, 2-substituted 3-(3-mercaptopropionyl)thiazolidine-4 carboxylic acids, L-cysteine, angiotensin converting enzyme inhibitors

Abstract

The natural amino acid L-cysteine, commercially available aldehydes, and 3-(acetylsulfanyl)propionyl chloride were used for the synthesis of 2-substituted (2R,4R)-3-(3-mercaptopropionyl)thiazolidine-4‑carboxylic acids, potential antihypertensive drugs with angiotensin converting enzyme inhibiting action.

How to Cite
Ershov, A. Yu.; Nasledov, D. G.; Lagoda, I. V.; Shamanin, V. V. Chem. Heterocycl. Compd. 2014, 50, 1032. [Khim. Geterotsikl. Soedin. 2014, 1119.]

For this article in the English edition see DOI 10.1007/s10593-014-1560-x

Author Biography

A. Ю. Ершов, Institute of Macromolecular Compounds, Russian Academy of Sciences

Aндрей Юрьевич Ершов

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Published

2014-08-08

Issue

No. 7 (2014)

Section

Original Papers