INTERACTION OF 2-(1H-BENZIMIDAZOL-2-YL)THIENO[2,3-b]PYRIDIN-3-AMINES WITH <i>ortho</i>-FORMYLBENZOIC ACIDS
DOI:
https://doi.org/10.1007/1836Keywords:
2-(1H-benzimidazol-2-yl)thieno[2, 3-b]pyridin-3-amines, (5, 6-dihydropyrido[3", 2", 4', 5']thieno[3', 2', 4, 5]pyrimidino[1, 6-a]benzimidazol-6-yl)benzoic acids, (±)-isoindolo[1', 2, 3]pyrido[3", 6-a]benzimidazol-6(10bH)-ones, ortho-formylbenzoic acids, (pyrido[3", molecular structures, X-ray structural analysisAbstract
We describe a two-stage synthesis of heptacyclic structures, isoindolo[1',2':2,3]pyrido[3",2":4',5']-thieno[3',2':4,5]pyrimido[1,6-a]benzimidazol-6(10bH)-ones, and intermediates, 5,6-dihydropyrido-[3",2":4',5']thieno[3',2':4,5]pyrimido[1,6-a]benzimidazol-6-yl]benzoic acids, as products from the interaction of 3-amino-2‑benzimidazolylthieno[2,3-b]pyridines and ortho-formylbenzoic acids. 5,6‑Dihydropyrido[3",2":4',5']thieno[3',2':4,5]pyrimido[1,6-a]benzimidazol-6-yl]benzoic acids were shown to easily oxidize (aromatize) to the corresponding pyrido[3",2":4',5']thieno[3',2':4,5]pyrimido[1,6-a]-benzimidazol-6‑yl]benzoic acids. The molecular and crystal structures of 4-(methoxymethyl)-2-methylisoindolo-[1',2':2,3]pyrido[3",2":4',5']thieno[3',2':4,5]pyrimido[1,6-a]benzimidazol-6(10bH)-one and 2-[4‑(methoxymethyl)-2-methylpyrido[3",2":4',5']thieno[3',2':4,5]pyrimido[1,6-a]benzimidazol-6-yl]benzoic acid were studied by X-ray crystallography.
How to Cite
Vasilin, V. K.; Lukina, D. Yu.; Stroganova, T. A.; Krapivin, G. D. Chem. Heterocycl. Compd. 2015, 50, 1487. [Khim. Geterotsikl. Soedin. 2014, 1614.]
For this article in the English edition see DOI 10.1007/s10593-014-1615-z
