APPLICATION OF A BALL MILLING TECHNIQUE FOR THE CONDENSATION OF ANTHRANILIC HYDRAZIDES WITH AROMATIC ALDEHYDES TOWARDS 4-QUINAZOLINONE DERIVATIVES

Authors

  • T. Magyar University of Szeged, Hungary
  • F. Miklós University of Szeged, Hungary
  • L. Lázár University of Szeged, Hungary
  • F. Fülöp University of Szeged, Hungary

DOI:

https://doi.org/10.1007/1837

Keywords:

hydrazides, quinazolinones, ball milling reactions, mechanochemistry, solventless reactions

Abstract

An environmentally friendly method was applied to prepare anthranilic hydrazones and quinazolin-4(1H)-ones from anthranilic hydrazides and a number of aldehydes in solventless medium. The condensations proceeded smoothly under ball milling conditions at room temperature, and the products were obtained in high purity and yield.

How to Cite
Magyar, T.; Miklós, F.; Lázár, L.; Fülöp F. Chem. Heterocycl. Compd. 2015, 50, 1464. [Khim. Geterotsikl. Soedin. 2014, 1590.]

For this article in the English edition see DOI 10.1007/s10593-014-1611-3

Author Biographies

T. Magyar, University of Szeged, Hungary

Timea Magyar

F. Miklós, University of Szeged, Hungary

Ferenc Miklós

L. Lázár, University of Szeged, Hungary

L. Lázár

F. Fülöp, University of Szeged, Hungary

Ferenc Fülöp

Institute of Pharmaceutical Chemistry,

professor, head of Institute

Published

2014-10-23

Issue

Section

Original Papers