REACTION OF Α-OXOKETENES WITH 2-SUBSTITUTED BENZOTHIAZOLES AND BENZIMIDAZOLES: SYNTHESIS OF BENZO[4,5]THIAZOLO[3,2-<i>a</i>]PYRIDINONE AND <i>N</i>-(1,3-BENZOTHIAZOL-2-YL)-3-OXOPROPANAMIDE DERIVATIVES

Authors

  • Mahboobeh Zahedifar Department of Chemistry, Faculty of Science, University of Jiroft 364 Jiroft, Iran
  • Hassan Sheibani Department of Chemistry, Shahid Bahonar University of Kerman Iran

DOI:

https://doi.org/10.1007/2736

Keywords:

chlorocarbonyl phenyl ketene, 1, 3-dioxin-4-ones, Meldrum's acids, α-oxoketenes, 2-substituted benzothiazoles

Abstract

A fast and simple procedure for the synthesis of pyrimidinone derivatives via the cyclocondensation reactions of α-oxoketenes with 2-substituted benzothiazoles have been investigated. Acyl-substituted Meldrum's acids and 1,3-dioxin-4-one derivatives have been used as starting compounds for preparation of α-oxoketenes, which were used in the cycloaddition reactions with (benzothiazol-2-yl)acetonitrile and (benzimidazol-2-yl)acetonitrile giving good product yields. Also the reaction of (chlorocarbonyl)phenylketene with 2-(1,3-benzothiazol-2-yl)acetonitrile has been investigated.

How to Cite
Zahedifar, M.; Sheibani, H. Chem. Heterocycl. Compd. 2016, 52, 41. [Khim. Geterotsikl. Soedin. 2016, 52,41.]

For this article in the English edition see DOI 10.1007/s10593-016-1829-3

Downloads

Published

2016-02-08

Issue

Vol. 52 No. 1 (2016)

Section

Original Papers