RECENT ADVANCES IN THE SYNTHESIS AND APPLICATIONS OF OXAZOLO[5,4-<i>d</i>]PYRIMIDINES

Authors

  • Adam Mieczkowski Institute of Biochemistry and Biophysics, Polish Academy of Sciences, 5a Pawinskiego St.,Warsaw 02-106
  • Bartosz Bieszczad Department of Chemistry, University of Warsaw, 1 Pasteura St., Warsaw 02-093

DOI:

https://doi.org/10.1007/3275

Keywords:

oxazolo[5, 4-d]pyrimidines, pyrimidine condesation, oxazole condensation, heterocycle synthesis, pharmacophore

Abstract

Modern methods of synthesis of oxazolo[5,4-d]pyrimidines published over the past 10 years are reviewed in the present communication.  The two main approaches include the synthesis via cyclization of pyrimidine derivatives resulted in the fused oxazole ring or by condensation of oxazole derivatives leading to fused pyrimidine rings.

Author Biography

Adam Mieczkowski, Institute of Biochemistry and Biophysics, Polish Academy of Sciences, 5a Pawinskiego St.,Warsaw 02-106

Department of Biophysics, Ph.D., assistant professor

Downloads

Published

2016-11-01

Issue

Vol. 52 No. 10 (2016)

Section

Heterocycles in Focus