THE SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF 5-(1<i>H</i>-1,2,3-TRIAZOL-4-YL)-1,2,4-OXADIAZOLE DERIVATIVES

Authors

  • Константин Ю. Кроленко National University of Pharmacy, 53 Pushkinska St., Kharkiv 61002
  • Сергей В. Власов National University of Pharmacy, 53 Pushkinska St., Kharkiv 61002
  • Ирина А. Журавель National University of Pharmacy, 53 Pushkinska St., Kharkiv 61002

DOI:

https://doi.org/10.1007/3291

Keywords:

1, 2, 3-triazole, piperidine ring, pyrrolidine ring, acylation, antimicrobial activity

Abstract

New 5-(1H-1,2,3-triazol-4-yl)-1,2,4-oxadiazole derivatives containing piperidine or pyrrolidine ring were synthesized and found to exhibit strong antimicrobial activity. A structure–activity study of the antimicrobial effect was performed for these compounds.

Authors: Konstantin Yu. Krolenko*, Sergiy V. Vlasov, Irina A. Zhuravel

Author Biographies

Константин Ю. Кроленко, National University of Pharmacy, 53 Pushkinska St., Kharkiv 61002

Аспирант кафедры токсикологической химии

Сергей В. Власов, National University of Pharmacy, 53 Pushkinska St., Kharkiv 61002

Доцент кафедры органической химии

Ирина А. Журавель, National University of Pharmacy, 53 Pushkinska St., Kharkiv 61002

Заведующий кафедрой токсикологической химии

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Published

2016-11-10

Issue

Vol. 52 No. 10 (2016)

Section

Original Papers