SIMPLE ONE-POT SYNTHESIS OF 5-(CHLOROMETHYL)ISOXAZOLES FROM ALDOXIMES AND 2,3-DICHLORO-1-PROPENE
Authors
Евгений В. Кондрашов
A. E. Favorsky Irkutsk Institute of Chemistry, Siberian Branch of the Russian Academy of Sciences,
1 Favorsky St., Irkutsk 664033, Russia
Нина С. Шатохина
A. E. Favorsky Irkutsk Institute of Chemistry, Siberian Branch of the Russian Academy of Sciences,
1 Favorsky St., Irkutsk 664033, Russia
A one-pot synthesis of 3-substituted 5-chloromethylisoxazoles from available starting aldoximes and 2,3-dichloro-1-propene, serving both as a solvent and reagent, is proposed. Excess 2,3-dichloro-1-propene is recovered after the reaction. The synthesis is effective for oximes of both aromatic and aliphatic aldehydes.
Author Biographies
Евгений В. Кондрашов, A. E. Favorsky Irkutsk Institute of Chemistry, Siberian Branch of the Russian Academy of Sciences,
1 Favorsky St., Irkutsk 664033, Russia
с.н.с. лаборатории галогенорганических соединений, Иркутский институт химии
Нина С. Шатохина, A. E. Favorsky Irkutsk Institute of Chemistry, Siberian Branch of the Russian Academy of Sciences,
1 Favorsky St., Irkutsk 664033, Russia
аспирант в лаборатории галогенорганических соединений, Иркутский институт химии
