DIAZAPYRENES: INTERACTION WITH NUCLEIC ACIDS AND BIOLOGICAL ACTIVITY

Authors

  • Андрей М. Жиров Stavropol Research Anti-Plague Institute, 13-15 Sovetskaya St., Stavropol 355035, Russia
  • Дмитрий А. Ковалев Stavropol Research Anti-Plague Institute, 13-15 Sovetskaya St., Stavropol 355035, Russia
  • Диана В. Ульшина Stavropol Research Anti-Plague Institute, 13-15 Sovetskaya St., Stavropol 355035, Russia
  • Сергей В. Писаренко Stavropol Research Anti-Plague Institute, 13-15 Sovetskaya St., Stavropol 355035, Russia
  • Олег П. Демидов North Caucasus Federal University, 1a Pushkina St., Stavropol 355017, Russia
  • Иван В. Боровлев North Caucasus Federal University, 1a Pushkina St., Stavropol 355017, Russia

DOI:

https://doi.org/10.1007/5425

Keywords:

diazapyrene, DNA, naphthalenediimide, RNA, biological activity, intercalation, G-quadruplex

Abstract

The review summarizes data on the practical aspects of the interaction of nucleic acids with diazapyrene derivatives. The information on biological activity is given and the probable mechanisms underlying the action of diazapyrenes are analyzed. It contains 119 references.

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Published

2020-07-10

Issue

Vol. 56 No. 6 (2020): Heterocyclic сompounds in medicinal chemistry

Section

Review Articles