RECENT ADVANCES IN THE SYNTHESIS AND BIOLOGICAL APPLICATIONS OF NORTOPSENTIN ANALOGS

Authors

  • Mona M. Kamel Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Cairo University, Kasr El-Aini St., Cairo 11562, Egypt
  • Mohamed K. Abdel-hameid Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Cairo University, Kasr El-Aini St., Cairo 11562, Egypt
  • Hala B. El-Nassan Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Cairo University, Kasr El-Aini St., Cairo 11562, Egypt
  • Eman A. El-Khouly Department of Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Cairo University, Kasr El-Aini St., Cairo 11562, Egypt

DOI:

https://doi.org/10.1007/5506

Keywords:

bisindolylimidazole, indole, marine alkaloids, nortopsentin, structural modifications.

Abstract

The present minireview summarizes the data published during the last decade (2012–2019) on the synthesis of nortopsentin analogs and the effect of the structural modifications on the biological activity of the synthesized analogs as antitumor, antifungal, and antiviral agents.

 

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Published

2020-05-28

Issue

Vol. 56 No. 5 (2020)

Section

Review Articles