SYNTHETIC APPROACHES TO PYRIDO[1,2-<i>a</i>]INDOLES

Authors

  • Igor L. Nikonov Department of Organic and Biomolecular Chemistry, Chemical Engineering Institute, Ural Federal University named after the first President of Russia B. N. Yeltsin, 19 Mira St., K-2, Yekaterinburg 620002, Russia; Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences, 22 S. Kovalevskoi / 20 Akademicheskaya St., Yekaterinburg 620108, Russia
  • Dmitry S. Kopchuk Department of Organic and Biomolecular Chemistry, Chemical Engineering Institute, Ural Federal University named after the first President of Russia B. N. Yeltsin, 19 Mira St., K-2, Yekaterinburg 620002, Russia; Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences, 22 S. Kovalevskoi / 20 Akademicheskaya St., Yekaterinburg 620108, Russia
  • Grigory V. Zyryanov Department of Organic and Biomolecular Chemistry, Chemical Engineering Institute, Ural Federal University named after the first President of Russia B. N. Yeltsin, 19 Mira St., K-2, Yekaterinburg 620002, Russia; Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences, 22 S. Kovalevskoi / 20 Akademicheskaya St., Yekaterinburg 620108, Russia
  • Oleg N. Chupakhin Department of Organic and Biomolecular Chemistry, Chemical Engineering Institute, Ural Federal University named after the first President of Russia B. N. Yeltsin, 19 Mira St., K-2, Yekaterinburg 620002, Russia Postovsky Institute of Organic Synthesis, Ural Branch of the Russian Academy of Sciences, 22 S. Kovalevskoi / 20 Akademicheskaya St., Yekaterinburg 620108, Russia

DOI:

https://doi.org/10.1007/5727

Abstract

The review presents the main methods for the synthesis of pyrido[1,2-a]indoles and their annulated and conjugated derivatives over the past 10 years. The approaches are divided into three groups depending on the
starting compounds: construction of the pyridine nucleus on the indole fragment, cyclization using benzylsubstituted pyridines, and formally one-step process via aryne intermediates.

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Published

2020-10-14

Issue

Vol. 56 No. 9 (2020)

Section

Heterocycles in Focus