SYNTHESIS OF CONDENSED PYRROLO[<i>b</i>]PYRAZINES

Abstract

Reaction of 2,3-dichloro-5,6-dicyanopyrazine with α-azahetarylacetonitriles gives α-(3-chloro-5,6-dicyanopyrazin-2-yl)-α-(2-azahetaryl)acetonitriles. Subsequent heating in pyridine causes an intramolecular cyclization to yield condensed pyrrolo[b]pyrazines.

Authors: Yu. M. Volovenko and G. G. Dubinina.

English Translation in Chemistry of Heterocyclic Compounds, 1999, 35 (9), pp 1089-1093

http://link.springer.com/article/10.1007/BF02251802