NEW APPROACH TO THE SYNTHESIS OF SUBSTITUTED 5-ARYLCARBAMOYL-3-CYANO-6-METHYLPYRIDINE-2(1H)-THIONES. MOLECULAR AND CRYSTAL STRUCTURE OF 2-ALLYLTHIO-3-CYANO-5-(2-METHOXYPHENYLCARBAMOYL)-6-METHYL-4-(5-METHYL-2-FURYL)-1,4-DIHYDROPYRIDINE

Authors

  • В. Д. Дяченко Lugansk T. Shevchenko State Pedagogical University, Lugansk 91011
  • А. Н. Чернега Lugansk T. Shevchenko State Pedagogical University, Lugansk 91011

DOI:

https://doi.org/10.1007/8080

Keywords:

morpholinium 5-arylcarbamoyl-3-cyano-6-methyl-4-(5-methyl-2-furyl)-1, 4-dihydropyridine-2-thiolates, enamines of acetoacetanilides, (5-methyl-2-furfurylidene)cyanothioacetamide, pyridine-2(1H)-thiones, thioethers, alkylation, X-ray structural analysis

Abstract

Morpholinium 5-arylcarbamoyl-3-cyano-6-methyl-4-(5-methyl-2-furyl)-1,4-dihydropyridine-2-thiolates have been obtained by the interaction of enamines of acetoacetanilides with 5-methyl-2-furfurylidenecyanothioacetamide. Alkylation of  the salts gives thioethers and oxidation gives the corresponding substituted pyridine-2(1H)-thiones.  The structure of 2-allylthio-3-cyano-5-(2-methoxyphenylcarbamoyl)-6-methyl-4-(5-methyl-2-furyl)-1,4-dihydropyridine was studied by X-ray crystallographic analysis.

How to Cite
Dyachenko, V. D.; Chernega, A. N.  Chem. Heterocycl. Compd. 2006, 42, 45. [Khim. Geterotsikl. Soedin. 2006, 51.]

For this article in the English edition, see DOI 10.1007/s10593-006-0045-y

 

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Published

2023-09-20

Issue

No. 1 (2006)

Section

Original Papers