NVESTIGATION OF NAPHTHYRIDINES. 16. SYNTHESIS OF DERIVATIVES OF 2,5-DIOXO-1,2,5,6,7,8-HEXAHYDRO-1,6-NAPHTHYRIDINE-3-CARBOXYLIC ACIDS FROM ANILIDES (HYDRAZIDES) OF 6-OXO-2-STYRYLNICOTINIC ACIDS

Authors

  • А. Б. Деянов Perm State Pharmaceutical Academy, Perm 614600
  • М. Е. Коньшин Perm State Pharmaceutical Academy, Perm 614600
  • З. Н. Семенова Perm State Pharmaceutical Academy, Perm 614600

DOI:

https://doi.org/10.1007/8424

Keywords:

anilides, hydrazides, 2, 5-dioxo-1, 5, 6, 7, 8-hexahydro-1, 6-naphthyridines, 6-oxo-2-styrylnicotinic acids, cyclization

Abstract

Heating  anilides (hydrazides) of 5-cyano-6-oxo-2-styrylnicotinic acids in polyphosphoric acid (PPA) leads to amides of  7-aryl-2,5-dioxo-6-phenyl(amino)-1,2,5,6,7,8-hexahydro-1,6-naphthyridine-3-carboxylic acids, which on heating with perchloric acid in acetic acid give the corresponding acids.

How to Cite
Deyanov, A. B.; Konshin, M. E.; Semenova, Z. N.  Chem. Heterocycl. Compd. 2004, 40, 1560. [Khim. Geterotsikl. Soedin. 2004, 1809.]

For this article in the English edition, see DOI 10.1007/s10593-005-0099-2


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Published

2023-12-13

Issue

No. 12 (2004)

Section

Original Papers