STUDY OF NITROGEN- AND SULFUR-CONTAINING HETEROCYCLES. 54. PROPERTIES AND CONVERSIONS OF PYRIMIDO[4,5-<i>b</i>]-1,4-BENZOTHIAZEPINES. SYNTHESIS OF A NOVEL HETEROCYCLIC SYSTEM: PYRIMIDO[5,4-<i>c</i>]ISOQUINOLINE

Authors

  • Т. С. Сафонова Center for Drug Chemistry/All-Russian Scientific Research Pharmaceutical Chemistry Institute, Moscow 119815
  • М. П. Немерюк Center for Drug Chemistry/All-Russian Scientific Research Pharmaceutical Chemistry Institute, Moscow 119815
  • Н. А. Гринева Center for Drug Chemistry/All-Russian Scientific Research Pharmaceutical Chemistry Institute, Moscow 119815
  • А. Ф. Керемов Dagestan State University, Makhachkala 367010
  • О. С. Анисимова Center for Drug Chemistry/All-Russian Scientific Research Pharmaceutical Chemistry Institute, Moscow 119815
  • Н. П. Соловьева Center for Drug Chemistry/All-Russian Scientific Research Pharmaceutical Chemistry Institute, Moscow 119815

DOI:

https://doi.org/10.1007/8432

Keywords:

pyrimidyl aryl sulfides, pyrimido[4, 5-b]-1, 4-benzothiazepine, pyrimido[5, 4-c]isoquinoline

Abstract

We have studied some properties and conversions of  pyrimido[4,5-b]-1,4-benzothiazepines: reduction, oxidation, reactions with nucleophilic reagents (methanol, hydrazine, hydroxylamine, o-methylhydroxylamine, and thiosemicarbazide). We have synthesized derivatives of a novel heterocyclic system: pyrimido[5,4-c]isoquinoline.

How to Cite
Safonova, T. S.; Nemeryuk, M. P.; Grineva, N. A.; Keremov, A. F.; Anisimova, O. S.; Solov'eva, N. P.  Chem. Heterocycl. Compd. 2004, 40, 1609. [Khim. Geterotsikl. Soedin. 2004, 1863.]

For this article in the English edition, see DOI 10.1007/s10593-005-0105-8


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Published

2023-12-15

Issue

No. 12 (2004)

Section

Original Papers