SYNTHESIS OF 2-SUBSTITUTED AND 2,3-DISUBSTITUTED QUINAZOLIN-4-ONES CONTAINING A STERICALLY HINDERED PHENOL RESIDUE

Authors

  • В. И. Келарев I. M. Gubkin Russian State Oil and Gas University, Moscow 117917
  • М. А. Силин I. M. Gubkin Russian State Oil and Gas University, Moscow 117917
  • В. Н. Кошелев I. M. Gubkin Russian State Oil and Gas University, Moscow 117917
  • О. А. Борисова I. M. Gubkin Russian State Oil and Gas University, Moscow 117917

Keywords:

azomethines, N-acylhydrazones, carboxylic acid imino esters, sterically hindered phenols, thiosemicarbazones, quinazolin-4-ones, condensation

Abstract

A series of 2-substituted and 2,3-disubstituted quinazolin-4-ones containing a 3,5-di(tert-butyl)-4-hydroxyphenyl group has been synthesized. They were prepared by the condensation of carboxylic acid imino ester hydrochlorides containing the indicated fragment with ethyl anthranilate and also by the reaction of azomethines, N-acylhydrazones, or the 4-phenylthiosemicarbazone of 3,5-di(tert-butyl)-4-hydroxybenzaldehyde with 2-methyl-4H-2,1-benzoxazin-4-one.

How to Cite
Kelarev, V. I.; Silin, M. A.; Koshelev, V. N.; Borisova, O. A. Chem. Heterocycl. Compd. 2004, 40, 603. [Khim. Geterotsikl. Soedin. 2004, 715.]

For this article in the English edition, see DOI 10.1023/B:COHC.0000037317.38046.fc

Published

2004-05-25

Issue

Section

Original Papers