CONDENSED ISOQUINOLINES. 16. ENAMINE PROPERTIES OF BENZO[4,5]IMIDAZO[1,2-<i>b</i>]ISOQUINOLIN-11(5H)-ONE IN TERMS OF ITS ACYLATION REACTIONS

Authors

  • Л. М. Потиха Taras Shevchenko National University, Kiev 01033
  • Н. В. Школьная Taras Shevchenko National University, Kiev 01033
  • В. М. Кисeль Taras Shevchenko National University, Kiev 01033
  • В. А. Ковтуненко Taras Shevchenko National University, Kiev 01033

Keywords:

heterocyclic enamines, enamines with a secondary nitrogen atom, benzo[4,5]imidazo[1,2-b]isoquinolin-11(5H)-one and 7H-2a,6b-diazabenzo[b]cyclopenta[l,m]fluorene-1,7(2H)-dione derivatives, acylation

Abstract

A study has shown that the acylation of benzo[4,5]imidazol[1,2-b]isoquinolin-11(5H)-one occurs at N(5) or at C(6) depending on the nature of the acylating reagent and the reaction conditions. It was found that principally C-acylation takes place in the absence of base. The reaction with α-halo-substituted carboxylic acid chlorides leads to the formation of C-acylated products which are converted to derivatives of the novel heterocyclic system 7H-2a,6b-diazabenzo[b]cyclopenta[l,m]fluorene-1,7(2H)-dione in the presence of base.

How to Cite
Potikha, L. M.; Shkilna, N. V.; Kisil, V. M.; Kovtunenko, V. O. Chem. Heterocycl. Compd. 2004, 40, 603. [Khim. Geterotsikl. Soedin. 2004, 715.]

For this article in the English edition, see DOI 10.1023/B:COHC.0000037316.62290.46

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Published

2004-05-25

Issue

No. 5 (2004)

Section

Original Papers