A REACTION OF 2-CARBONYL-SUBSTITUTED 1<i>H</i>-BENZO[<i>f</i>]CHROMENES WITH <i>N</i>-ARYLAMIDES OF CYANOACETIC ACID

Authors

  • Дмитрий В. Осипов Samara State Technical University, 244 Molodogvardeyskaya St., Samara 443100, Russia
  • Павел Красников Samara State Technical University, 244 Molodogvardeyskaya St., Samara 443100, Russia
  • Алина А. Артеменко Samara State Technical University, 244 Molodogvardeyskaya St., Samara 443100, Russia

Keywords:

active methylene nitriles, N-aryl-2-cyanoacetamides, 1H-benzo[f]chromenes, 2-pyridones, Dimroth rearrangement, Michael reaction, Thorpe–Ziegler cyclization

Abstract

A reaction of 2-trifluoroacetyl-1H-benzo[f]chromenes with N-arylamides of cyanoacetic acid led to the synthesis of a series of 2-oxo-6trifluoromethylpyridine-3-carboxamides as products of a cascade of the carbo-Michael reaction, Thorpe–Ziegler cyclization, and Dimroth rearrangement. In the case of 1H-benzo[f]chromene-2-carbaldehydes, the corresponding Knoevenagel adducts were isolated.

 

Author Biography

Павел Красников, Samara State Technical University, 244 Molodogvardeyskaya St., Samara 443100, Russia

https://www.researchgate.net/profile/P-Krasnikov

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Published

2024-05-28

Issue

Vol. 60 No. 3/4 (2024)

Section

Original Papers