SYNTHESIS OF 9-ARYL-6,6-DIMETHYL-5,6,7,9-TETRAHYDRO-1,2,4-TRIAZOLO-[5,1-<i>b</i>]QUINAZOLIN-8(4H)ONES

Authors

  • В. В. Липсон Ukraine National Institute for the Pharmacology of Endocrine Disorders, Kharkov 61002
  • С. М. Десенко V. N. Karazin National University, Kharkov 61070
  • М. Г. Широбокова Ukraine National Institute for the Pharmacology of Endocrine Disorders, Kharkov 61002
  • В. В. Бородина Ukraine National Institute for the Pharmacology of Endocrine Disorders, Kharkov 61002

Keywords:

3-amino-1,2,4-triazole, arylidene derivatives of dimedone, partially hydrogenated quinazoline systems, cyclocondensation

Abstract

The reaction of 3-amino-1,2,4-triazole with arylidene derivatives of dimedone and their potential synthetic equivalents leading to the formation of 9-aryl-6,6-dimethyl-5,6,7,9-tetrahydro-1,2,4-triazolo-[5,1-b]quinazolin-8(4H)ones has been studied. The direction of heterocyclization has been established, and the possible mechanisms for the formation of the pyrimidine heterocycle have been analysed.

How to Cite
Lipson, V. V.; Desenko, S. M.; Shirobokova, M. G.; Borodina, V. V. Chem. Heterocycl. Compd. 2003, 39, 1213. [Khim. Geterotsikl. Soedin. 2003, 1383.]

For this article in the English edition, see DOI 10.1023/B:COHC.0000008269.69460.ac

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Published

2003-09-25

Issue

No. 9 (2003)

Section

Original Papers