4,4-ДИАЛКИЛЗАМЕЩЕННЫЕ 6-ОКСО-3,5-ДИЦИАНО-1,4,5,6-ТЕТРАГИДРОПИРИДИН-2-ТИОЛАТЫ N-МЕТИЛМОРФОЛИНИЯ И НЕКОТОРЫЕ ИХ СВОЙСТВА

Authors

  • В. Д. Дяченко Taras Shevchenko State Pedagogical University, Lugansk 91011
  • А. А. Никишин Taras Shevchenko State Pedagogical University, Lugansk 91011
  • А. Н. Чернега Institute of Organic Chemistry, National Academy of Sciences of Ukraine, Kiev 02094

Keywords:

4,4-dialkyl-substituted 3,5-dicyano-6-oxo-1,4,5,6-tetrahydropyridine-2-thiolates, alkylation, acylation, bromination, condensation, nucleophilic substitution, X-ray crystallographic analysis, cyclization

Abstract

4,4-Dialkyl-substituted N-methylmorpholinium 3,5-dicyano-6-oxo-1,4,5,6-tetrahydropyridine-2-thiolates were synthesized by the condensation of 2-alkyl-2-cyanoethyl crotonates with cyanothioacetamide and N-methylmorpholine. They were used for the production of substituted 2-alkylthio-1,4,5,6-tetrahydropyridines, 2-acetylthio-1,4,5,6,-tetrahydropyridine, 6-hydrazino-1,4,5,6-tetrahydropyridine, and 2,3,4,5,6,7-hexahydrothiazolo[3,2-a]pyridine. The structure of 6-bromo-3-bromomethyl-6,8-dicyano-7,7-dimethyl-2,3,4,5,6,7-hexahydrothiazolo[3,2-a]pyridine was proved by X-ray crystallographic analysis.

How to Cite
Dyachenko, V. D.; Nikishin, A. A.; Chernega, A. N. Chem. Heterocycl. Compd. 2003, 39, 1153. [Khim. Geterotsikl. Soedin. 2003, 1316.]

For this article in the English edition, see DOI 10.1023/B:COHC.0000008259.47550.0b

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Published

2003-09-25

Issue

No. 9 (2003)

Section

Original Papers