SYNTHESIS OF N-SUBSTITUTED DERIVATIVES OF (5-AMINO-2-METHYL-1H-INDOL-3-YL)ACETIC ACID

Authors

  • С. А. Маклаков Novomoskovsk Institute of the D. I. Mendeleev Russian University of Chemical Technology, Novomoskovsk 301670
  • Ю. И. Смушкевич D. I. Mendeleev Russian University of Chemical Technology, Moscow 125047
  • И. В. Магедов Moscow K. A. Timiryazev Agricultural Academy, Moscow 127550

Keywords:

(5-amino-2-methyl-1H-indol-3-yl)acetic acid, N-(4-hydrazinophenyl)acetamide, indole, indomethacin, Fischer reaction

Abstract

A method has been developed for obtaining indole compounds containing an amino group in the benzene ring by the indolization of ethyl levulinate p-acetaminophenylhydrazone. A series of derivatives of (5-amino-2-methyl-1H-indol-3-yl)acetic acid at the 5-amino group has been synthesized.

How to Cite
Maklakov, S. A.; Smushkevich, Yu. I.; Magedov, I. V. Chem. Heterocycl. Compd. 2002, 38, 539. [Khim. Geterotsikl. Soedin. 2002, 619.]

For this article in the English edition, see DOI https://doi.org/10.1023/A:1019500911047

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Published

2002-05-25

Issue

No. 5 (2002)

Section

Original Papers