ISOMERIC AND TAUTOMERIC STRUCTURES OF AMINO-IMINO 5<i>H</i>-PYRROLO[3,4-<i>b</i>]PYRIDINE DERIVATIVES REVISITED

Authors

  • Olga V. Ovdiichuk Faculty of Chemistry, Taras Shevchenko National University of Kyiv, 64/13 Volodymyrska St., Kyiv 01601
  • Volodymyr A. Tkachuk Faculty of Chemistry, Taras Shevchenko National University of Kyiv, 64/13 Volodymyrska St., Kyiv 01601. Enamine Ltd., 78 Winston Churchill St., Kyiv 02094
  • Andriy V. Kozytskiy Enamine Ltd., 78 Winston Churchill St., Kyiv 02094. ChemBioCenter, Taras Shevchenko National University of Kyiv, 64/13 Volodymyrska St., Kyiv 01601
  • Olga V. Hordiyenko Faculty of Chemistry, Taras Shevchenko National University of Kyiv, 64/13 Volodymyrska St., Kyiv 01601 https://orcid.org/0000-0002-4749-7195

Keywords:

pyridine-2,3-dicarbonitrile, 5H-pyrrolo[3,4-b]pyridine, ring closure, regioisomerism, tautomerism

Abstract

The research of the interaction of pyridine-2,3-dicarbonitrile with aliphatic and aromatic primary amines has been carried out. The study of the structure of the products by the means of 1H, 13C NMR, NOESY, 1H–15N HMBC experiments has shown that the reaction with aromatic amines proceeds regioselectively with the formation of 5H-pyrrolo[3,4-b]pyridine derivatives.

Author Biography

Olga V. Hordiyenko, Faculty of Chemistry, Taras Shevchenko National University of Kyiv, 64/13 Volodymyrska St., Kyiv 01601

Dr.,

Associate Professor, Faculty of Chemistry

Taras Shevchenko National University of Kyiv

64/13 Volodymyrs’ka Str.

01601, Kyiv

Ukraine

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Published

2025-09-18

Issue

Vol. 61 No. 5/6 (2025)

Section

Short Communications