New methods for the synthesis of alkyl-substituted 6-oxo-3-cyano-1,4,5,6-tetrahydropyridine-2-thiolates and their derivatives

Authors

  • C. Г. Кривоколыско T. G. Shevchenko Lugansk State Pedagogical Institute, Lugansk 348011
  • B. Д. Дяченко T. G. Shevchenko Lugansk State Pedagogical Institute, Lugansk 348011
  • В. П. Литвинoв N. D. Zelinskii Institute of Organic Chemistry, Russian Academy of Sciences, Moscow 117913

Abstract

Condensation of formaldehyde or acetaldehyde with cyanothioacetamide and cyanoacetic ester in the presence of organic bases afforded 6-oxo-3,5-dicyano-4-R-1,4,5,6-tetrahydropyridine-2-thiolates (R=H, CH3), which were utilized in the synthesis of substituted 2-alkylthiopyridones and thieno[2,3-b]pyridone.

How to Cite
Krivokolysko, S. G.; Dyachenko, V. D.; Litvinov, V. P. Chem. Heterocycl. Compd. 1998, 34, 1174. [Khim. Geterotsikl. Soedin. 1998, 34, 1381.]

For this article in the English edition, see DOI https://doi.org/10.1007/BF02319496

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Published

1998-10-25

Issue

No. 10 (1998)

Section

Original Papers