Formation of pyrrolo[2,3-<i>f</i>]quinolines from substituted 5-methyl-6-aminoindoles by the Combes reaction

Authors

  • C. А. Ямашкин M. E. Evsev'ev Mordovian State Pedagogical Institute, Saransk 430007
  • Н. Я. Кучеренко M. E. Evsev'ev Mordovian State Pedagogical Institute, Saransk 430007
  • М. А. Юрoвская M. V. Lomonosov Moscow State University, Moscow 119899

Abstract

It is shown that the reaction of 2,3,5-trimethyl-6-aminoindole with 1,3-diketones is a convenient method for the preparation of angular 1H-pyrrolo[2,3-f]quinolines, while the presence of a methyl group on the pyrrolic nitrogen atom of the initial indole as a result of steric hindrance completely blocks cyclization to the corresponding pyrroloquinolines.

How to Cite
Yamashkin, S. A.; Kucherenko, N. Y.; Yurovskaya, M. A. Chem. Heterocycl. Compd. 1995, 31, 1299. [Khim. Geterotsikl. Soedin. 1995, 1499.]

For this article in the English edition, see DOI https://doi.org/10.1007/BF01168623

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Published

1995-11-25

Issue

No. 11 (1995)

Section

Original Papers