CONDENSED ISOQUINOLINES. 35. SYNTHESIS AND REACTIONS OF 4<i>H</i>-THIENO[3',4':5,6]PYRIMIDO[1,2-<i>b</i>]ISOQUINOLINE-4,11(5<i>H</i>)-DIONE

Authors

  • А. В. Задорожний Taras Shevchenko Kiev National University, Kiev 01033
  • В. А. Ковтуненко Taras Shevchenko Kiev National University, Kiev 01033
  • А. В. Туров Taras Shevchenko Kiev National University, Kiev 01033

DOI:

https://doi.org/10.1007/4916

Keywords:

positional isomers, derivatives of 4H-thieno[3', 4', 5, 6]pyrimido[1, 2-b]isoquinoline-4, 11(5H)-dione, nucleophilic substitution, calculation of biological activity, UV spectra, cyclization

Abstract

Derivatives of the previously unknown tetracyclic system 4H-thieno[3',4':5,6]pyrimido[1,2-b]iso-quinoline-4,11(5H)-dione have been synthesized. A comparison of the spectral characteristics and the biological activities of these compounds has been carried out, and also of their positional isomers and benzene isosteres. The differences, associated with the position of the sulfur atom, are most reflected in their electronic spectra.

How to Cite
Zadorozhny, A. V.; Kovtunenko, V. A.; Turov, A. V. Chem. Heterocycl. Compd. 2010, 46, 957. [Khim. Geterotsikl. Soedin. 2010, 1185.]

For this article in the English edition see DOI 10.1007/s10593-010-0608-9

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Published

2019-01-15

Issue

No. 8 (2010)

Section

Original Papers