REACTIONS OF PHENOL AND ITS DERIVATIVES WITH LEVOGLUCOSENONE

Authors

  • Лилия Х. Файзуллина Ufa Institute of Chemistry, Ufa Federal Research Center, Russian Academy of Sciences, 71 Oktyabrya Ave., Ufa 450054
  • Лилия Ш. Карамышева Ufa Institute of Chemistry, Ufa Federal Research Center, Russian Academy of Sciences, 71 Oktyabrya Ave., Ufa 450054
  • Юлия А. Халилова Ufa Institute of Chemistry, Ufa Federal Research Center, Russian Academy of Sciences, 71 Oktyabrya Ave., Ufa 450054
  • Шамиль М. Салихов Ufa Institute of Chemistry, Ufa Federal Research Center, Russian Academy of Sciences, 71 Oktyabrya Ave., Ufa 450054
  • Фарид А. Валеев Ufa Institute of Chemistry, Ufa Federal Research Center, Russian Academy of Sciences, 71 Oktyabrya Ave., Ufa 450054

DOI:

https://doi.org/10.1007/7200

Keywords:

levoglucosenone, phenol, resorcinol, antioxidant activity, electrophilic substitution

Abstract

The effect of hydroxy-, methyl-, and benzyloxy substituents in the corresponding phenol derivatives on the result of the Michael addition to levoglucosenone in the presence of AlCl3 or FeCl3 was studied. The reaction of phenols containing hydroxyl and methyl groups in the ortho position with levoglucosenone concludes with spontaneous ketalization of the carbohydrate keto group. The obtained compounds are promising in terms of studying their structure–activity relationship.

Authors: Liliya Kh. Faizullina*, Liliya Sh. Karamysheva1, Yuliya A. Khalilova1, Shamil M. Salikhov, Farid A. Valeev

Author Biography

Лилия Х. Файзуллина, Ufa Institute of Chemistry, Ufa Federal Research Center, Russian Academy of Sciences, 71 Oktyabrya Ave., Ufa 450054

к.х.н. по специальности 02.00.03 органическая химия, доцент, старший научный сотрудник лаборатории фармакофорных циклических систем

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Published

2023-05-31

Issue

Vol. 59 No. 4/5 (2023)

Section

Original Papers