DISORDERING IN THE CRYSTAL STRUCTURES OF THIENYLGERMATRANES

Abstract

The crystal structure of a  series  of  thienylgermatranes has been studied using X-ray diffraction. Disorder of the thiophene ring in a 2-thienylgermatrane has been established. In the same positions of the  unit  cell  of  the  crystal there are found both molecules with an O(2)–Ge–C–S torsional angle of -166.8(4)° and molecules in which this angle is 14.0(4)°. The lengths of the transannular N→Ge bonds (2.183-2.283 Å) agrees in value with the values of crystalline germatrane structures with a Ge–C bond. The length of the transannular N→Ge bond (2.248 Å) in 4-(2-thienyl)phenylgermatrane (molecule A) is the largest amongst germatranes with a Ge–Car bond. Introduction of a second thiophene ring into the 2-thienylgermatrane molecule lowers the acute toxicity of the compound by about 27 times (LD50 for the 2,2'-bithienylgermatrane = 447 mg/kg).

How to Cite
Lukevics, E.; Ignatovich, L.; Belyakov, S.  Chem. Heterocycl. Compd. 2007, 43, 243. [Khim. Geterotsikl. Soedin. 2007, 299.]

For this article in the English edition see DOI 10.1007/s10593-007-0038-5