SYNTHESIS AND ALKYLATION OF N-METHYLMORPHOLINIUM 4-ARYL-3,5-DICYANO-6-OXO-1,4,5,6-TETRAHYDRO-2-PYRIDINETHIOLATES. MOLECULAR AND CRYSTAL STRUCTURE OF 4,5-<i>trans</i>-3,5-DICYANO-4-(2-METHOXYPHENYL)-2-METHYLTHIO-6-OXO-1,4,5,6-TETRAHYDROPYRIDINE

Authors

  • С. Г. Кривоколыско Taras Shevchenko Lugansk State Pedagogical University, 348011 Lugansk
  • В. Д. Дяченко Taras Shevchenko Lugansk State Pedagogical University, 348011 Lugansk
  • Э. Б. Русанов Institute of Organic Chemistry, National Academy of Sciences of Ukraine, 253660 Kiev
  • В. П. Литвинов N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, 117913 Moscow

Keywords:

aromatic aldehydes, substituted N-methylmorpholinium 1,4,5,6-tetrahydro-2-pyridinethiolates, cyanothioacetamide, ethyl cyanoacetate, X-ray diffraction analysis

Abstract

The reaction of aromatic aldehydes with cyanothioacetamide and ethyl cyanoacetate in the presence of N-methylmorpholine gives N-methylmorpholinium 4-aryl-3,5-dicyano-6-oxo-1,4,5,6-tetrahydro-2-pyridinethiolates, which are used in the synthesis of substituted 2-alkylthiotetrahydropyridines. X-ray diffraction analysis was used to study the structure of 4,5-trans-3,5-dicyano-4-(2-methoxyphenyl)-2-methylthio-6-oxo-1,4,5,6-tetrahydropyridine.

How to Cite
Krivokolysko, S. G.; Dyachenko, V. D.; Rusanov, E. B.; Litvinov, V. P. Chem. Heterocycl. Compd. 2001, 37, 477. [Khim. Geterotsikl. Soedin. 2001, 525.]

For this article in the English edition, see DOI https://doi.org/10.1023/A:1017656005767

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Published

2001-04-25

Issue

No. 4 (2001)

Section

Original Papers