Synthesis and properties of (4-carbamoylquinol-2-yl)cyanoacetic acids

Abstract

Reaction of 2-chlorocinchoninic acid anodes with malonodinitrile or cyanoacetic ester and potassium carbonate in refluxing DMF gives (4-carbamylquinol-2-yl)malonodinitriles and -cyanoacetic esters respectively. Using UV and PMR spectroscopy it was shown that they exist in the ylidene form, being stabilized in the latter case by a chelate type intramolecular hydrogen bond.

How to Cite
Mikhalev, A. I.; Konshin, M. E.; Vakhrin, M. I. Chem. Heterocycl. Compd. 1996, 32, 452. [Khim. Geterotsikl. Soedin. 1996, 519.]

For this article in the English edition, see DOI https://doi.org/10.1007/BF01165910