Synthesis of 2-phenylethynyl-1,3-dioxanes and their hydrolysis

Abstract

2-Phenylethynyl substituted 1,3-dioxanes were obtained by the reaction of 1,3-dioxanium salts with an lotsich reagent. It was shown that they are readily hydrolyzed with the formation of α-acerylenic ketones. A simple new method is proposed for the synthesis of the latter without isolating the intermediate 1,3-dioxanes using the reaction of 4 substituted 2-methyl(phenyl, furyl)-1,3-dioxanium salts with hydroxymethyl- and phenylethynylmagnesium bromide as examples.

How to Cite
Kosulina, T. P.; Kul'nevich, V. G. Chem. Heterocycl. Compd. 1996, 32, 169. [Khim. Geterotsikl. Soedin. 1996, 198.]

For this article in the English edition, see DOI https://doi.org/10.1007/BF01165440