BIOACTIVITIES AND STRUCTURAL STUDIES OF WITHANOLDES FROM <i>WITHIANIA SOMNIFЕRA</i>

Authors

  • S. Arshad Jamal H. E. J. Research Institute of Chemistry, University of Karachi, 75274, Karachi
  • Samina Qureshi H. E. J. Research Institute of Chemistry, University of Karachi, 75274, Karachi
  • Samina Noor Ali H. E. J. Research Institute of Chemistry, University of Karachi, 75274, Karachi
  • M. Iqbal Choudhary H. E. J. Research Institute of Chemistry, University of Karachi, 75274, Karachi
  • Rahman Atta-Ur H. E. J. Research Institute of Chemistry, University of Karachi, 75274, Karachi

Abstract

Four bioactive withanolides, withalactone (1), witbaoxylactone (2), quresimine-A (4β-hydrоxу, 3β-mеthoхy-5β,6β-ероxу-(22R)-withа-24-enolide) (3) and quresimine-B (4β,27-dihуdroxу-Зβ-mеthoxу- 5β,6β-epoxy-(22R)-witha-24-enolide (4) have been isolated from the herbs of Withiania somnifera, Dunal (Sоlanaceae). The elucidation of their structures is based on extensive spectroscopic studies, such as 1Н-NMR, СОSY-45°, HMBC, HMQC, HOHAHA, E.I.; FAB (+ ve) and HR MS etc.

How to Cite
Arshad Jamal, S.; Qureshi, S.; Noor Ali, S.; Iqbal Choudhary, M.; Atta-Ur, R. Chem. Heterocycl. Compd. 1995, 31, 1047. [Khim. Geterotsikl. Soedin. 1995, 1200.]

For this article in the English edition, see DOI https://doi.org/10.1007/BF01165050

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Published

1995-09-25

Issue

No. 9 (1995)

Section

Original Papers