NOVEL METHOD OF SYNTHESIS OF 2,3-DIHYDROFURO[3,2-<i>h</i>]QUINOLINES

Abstract

Reaction of 8-hydroxy-7-piperidinomethylquinoline with pyridinium ylides gave 2-acyl-2,3-dihydro-furo[3,2-h]quinolines. The formation of a highly electrophilic quinoline type o-quinone methide is proposed as an intermediate.

Authors: V. A. Osyanin, D. V. Osipov, and Yu. N. Klimochkin.

English Translation in Chemistry of Heterocyclic Compounds, 2012, 48 (7), pp 993-996

http://link.springer.com/article/10.1007/s10593-012-1090-3