DEALKYLATION OF QUATERNARY 1-ALKYLAZOLO[<i>a</i>]PYRIDINIUM SALTS

Authors

  • Л. М. Потиха Taras Shevchenko Kyiv National University
  • А. Р. Турелик Taras Shevchenko Kyiv National University
  • А. В. Шелепюк Taras Shevchenko Kyiv National University
  • В. А. Ковтуненко Taras Shevchenko Kyiv National University

DOI:

https://doi.org/10.1007/1261

Keywords:

imidazo[1, 2-a]pyridine, pyrido[1, 2-a]benzimidazole, [1, 2, 4]triazolo[4, 3-a]pyridine, alkylation, cyclization, dealkylation

Abstract

A convenient method is proposed for the preparation of new derivatives of free heterocyclic bases of imidazo[1,2-a]pyridine, pyrido[1,2-a]benzimidazole, and [1,2,4]triazolo[4,3-a]pyridine series. This method entails the dealkylation of N-(2-cyanoethyl)- or N-benzylazolopyridinium quaternary salts in the presence of bases and reaction with ammonium formate in the presence of Pd/C, respectively.

Authors: L. M. Potikha, A. R. Turelik, A. V. Shelepyuk, and V. A. Kovtunenko.

English translation in Chemistry of Heterocyclic Compounds, 2012, 48 (2), pp 343-354

http://link.springer.com/article/10.1007/s10593-012-0995-1

 

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Published

2013-11-29

Issue

No. 2 (2012)

Section

Original Papers