INTERMOLECULAR DIRECT ARYLATION OF FIVE-MEMBERED RING HETEROCYCLES BY NON-ACTIVATED ARYL CHLORIDES

Abstract

Use of non-activated aryl chloride electrophiles in direct arylation of carbon–hydrogen bonds in five-membered ring heterocycles is described. Specifically, palladium-, ruthenium-, and nickel-catalyzed transformations, as well as reactions proceeding via benzyne intermediates are discussed.

Also published in Chemistry of Heterocyclic Compounds, 2012, 48 (1), pp 21-26

http://link.springer.com/article/10.1007/s10593-012-0963-9