SYNTHESIS OF [(THIAZOL-2-YLAMINO)METHYLENE]BISPHOSPHONIC ACIDS
DOI:
https://doi.org/10.1007/1397Keywords:
bisphosphonate, thiazole, cyclizationAbstract
A method for the synthesis of [(thiazol-2-ylamino)methylene]bisphosphonic acids from (aminomethylene)-bisphosphonic acid through 3-N-unsubstituted (thioureidomethylene)bisphosphonic acid was proposed.
Authors: A. L. Chuiko, L. P. Filonenko, and M. O. Lozinskii.
English translation in Chemistry of Heterocyclic Compounds, 2011, 47 (9), pp 1137-1140