A CONVENIENT METHOD FOR THE SYNTHESIS OF 1-R-1,2,3,4-TETRAHYDROBENZOTHIENO[2,3-<i>c</i>]PYRIDINE DERIVATIVES

Authors

  • В. С. Толкунов L. M. Litvinenko Institute of Physical Organic and Coal Chemistry, National Academy of Sciences of Ukraine
  • А. Б. Ересько L. M. Litvinenko Institute of Physical Organic and Coal Chemistry, National Academy of Sciences of Ukraine
  • А. В. Мазепа A. V. Bogatsky Physico Chemical Institute, National Academy of Sciences of Ukraine
  • С. В. Толкунов L. M. Litvinenko Institute of Physical Organic and Coal Chemistry, National Academy of Sciences of Ukraine

DOI:

https://doi.org/10.1007/1402

Keywords:

2-(1-benzothiophen-3-yl)ethylamine, 1, 2, 3, 4-tetrahydrobenzothieno[2, 3-c]pyridine, triisopropylchlorosilane, Pictet-Spengler reaction

Abstract

New 1-R-2-methyl-1,2,3,4-tetrahydrobenzothieno[2,3-c]pyridine derivatives have been obtained by cyclization of 2-(1-benzothiophen-3-yl)ethylamines with aromatic and heteroaromatic aldehydes in the presence of triisopropylchlorosilane.

Authors: V. S. Tolkunov, A. B. Eresko, A. V. Mazepa, and S. V. Tolkunov.

English translation in Chemistry of Heterocyclic Compounds, 2011, 47 (9), pp 1170-1175

http://link.springer.com/article/10.1007/s10593-011-0888-8

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Published

2013-12-18

Issue

No. 9 (2011)

Section

Original Papers