CYCLO(L-PRO-L-TYR), THE FUNGICIDE ISOLATED FROM <i>LYSOBACTER CAPSICI</i> AZ78: A STRUCTURE–ACTIVITY RELATIONSHIPS STUDY

Authors

  • A. Cimmino Università di Napoli Federico II
  • G. Puopolo Research and Innovation Center, Fondazione Edmund Mach
  • M. Perazzolli Research and Innovation Center, Fondazione Edmund Mach
  • A. Andolfi Università di Napoli Federico II
  • D. Melck Institute of Biomolecular Chemistry, CNR, Comprensorio Olivetti, Edificio 70, Via Campi Flegrei 34, 80078 Pozzuoli, Italy
  • I. Pertot Research and Innovation Center, Fondazione Edmund Mach
  • A. Evidente Università di Napoli Federico II

DOI:

https://doi.org/10.1007/1439

Keywords:

Lysobacter capsici, cyclo(L-Pro-L-Tyr), anti-oomycete activity, SAR

Abstract

Four hemisynthetic derivatives were prepared from maculosin (cyclo(L-Pro-L-Tyr)), isolated from Lysobacter capsici AZ78 and having anti-oomycete activity against some fungi pathogenic crop plants. A very strong antifungal activity was showed by the azido derivatives of maculosin, which could have pratical application in agriculture as safe fungicide.

How to Cite
Cimmino, A.; Puopolo, G.; Perazzolli, M.; Andolfi, A.; Melck, D.; Pertot, I.; Evidente, A. Chem. Heterocycl. Compd. 2014, 50, 290. [Khim. Geterotsikl. Soedin. 2014, 317.]

For this article in the English edition see DOI 10.1007/s10593-014-1475-6

Author Biography

A. Evidente, Università di Napoli Federico II

Dipartimento di Scienze Chimiche

Downloads

Published

2014-02-20

Issue

No. 2 (2014)

Section

Letters to the Editor