SYNTHESIS OF 1-FUNCTIONALIZED IMIDAZO[1,5-<i>а</i>]PYRAZOLO[5,1-<i>с</i>]PYRAZINES

Authors

  • Евгений Владимирович Гринишин Institute of Organic Chemistry, National Academy of Sciences of Ukraine; National University of ''Kyiv-Mohyla Academy''
  • Андрей Викторович Больбут Institute of Organic Chemistry, National Academy of Sciences of Ukraine; Enamine Ltd.
  • Михаил Владимирович Вовк Institute of Organic Chemistry, National Academy of Sciences of Ukraine

DOI:

https://doi.org/10.1007/4761

Keywords:

4-chloropyrazolo[1, 5-a]pyrazines, ethyl isocyanoacetate, imidazo[1, 5-a]pyrazolo[5, 1-с]pyrazines, functional derivatives

Abstract

4-Chloropyrazolo[1,5-a]pyrazines react with ethyl isocyanoacetate to form ethyl imidazo[1,5-a]pyrazolo[5,1-c]pyrazine-1-carboxylates, hydrolysis of which yields the corresponding acids and reduction gives alcohols oxidized by the action of the Dess–Martin reagent to aldehydes.

Authors: Nazar M. Tsizorik, Yevhenii V. Hrynyshyn, Andriy V. Bol'but, Mykhailo V. Vovk

 

 

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Published

2018-12-12

Issue

Vol. 54 No. 11 (2018)

Section

Short Communications