SYNTHESIS OF CYCLIC D-(+)-CAMPHORIC ACID IMIDES AND STUDY OF THEIR ANTIVIRAL ACTIVITY

Authors

  • Vladimir V. Chernyshov N. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch of Russian Academy of Sciences, 9 Akademika Lavrentieva Ave., Novosibirsk 630090, Russia Novosibirsk State University, 2 Pirogova St., Novosibirsk 630090, Russia
  • Olga I. Yarovaya N. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch of Russian Academy of Sciences, 9 Akademika Lavrentieva Ave., Novosibirsk 630090, Russia Novosibirsk State University, 2 Pirogova St., Novosibirsk 630090, Russia
  • Roman Yu. Peshkov Novosibirsk State University, 2 Pirogova St., Novosibirsk 630090, Russia
  • Nariman F. Salakhutdinov N. N. Vorozhtsov Novosibirsk Institute of Organic Chemistry, Siberian Branch of Russian Academy of Sciences, 9 Akademika Lavrentieva Ave., Novosibirsk 630090, Russia Novosibirsk State University, 2 Pirogova St., Novosibirsk 630090, Russia

DOI:

https://doi.org/10.1007/5678

Keywords:

D-( )-camphoric acid, D-( )-camphoric acid anhydride, imides, antiviral activity, cytotoxicity.

Abstract

Several D-(+)-camphoric acid imides, not previously described in the literature, were synthesized with good yields. The synthesis of previously known imides was improved. The cytotoxicity and antiviral activity of all synthesized imides were studied.

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Published

2020-07-10

Issue

Vol. 56 No. 6 (2020): Heterocyclic сompounds in medicinal chemistry

Section

Original Papers