FEATURES OF THE REACTION OF 1-AMINO-2-NITROGUANIDINE WITH ISATINS. SYNTHESIS OF [1,2,4]TRIAZINO[5,6-<i>b</i>]INDOLES

Authors

  • Татьяна П. Ефимова Herzen State Pedagogical University of Russia, 48 Moyka River Embankment, Saint Petersburg 191186, Russia
  • Мария П. Иванова Herzen State Pedagogical University of Russia, 48 Moyka River Embankment, Saint Petersburg 191186, Russia
  • Тамара А. Новикова Herzen State Pedagogical University of Russia, 48 Moyka River Embankment, Saint Petersburg 191186, Russia
  • Сергей В. Макаренко Herzen State Pedagogical University of Russia, 48 Moyka River Embankment, Saint Petersburg 191186, Russia

DOI:

https://doi.org/10.1007/6176

Keywords:

1-amino-2-nitroguanidine, isatin, isatin β-derivatives, 1, 2, 4-triazines, triazinoindoles, E/Z isomerism.

Abstract

Reactions of 1-amino-2-nitroguanidine with isatins leading to the formation of new β-(2-nitro)guanidinohydrazones of isatin, which exist as E/Z-isomers in regards to the azomethine fragment, were studied. It was found that the conditions of the reactions of 1-amino-2nitroguanidine with isatins affect the geometry of the formed hydrazones. Conditions for the cyclization of the obtained (Z)-β-(2-nitro)guanidinohydrazones leading to 3-nitroimino-containing [1,2,4]triazino[5,6-b]indoles were proposed.

 

Author Biography

Татьяна П. Ефимова, Herzen State Pedagogical University of Russia, 48 Moyka River Embankment, Saint Petersburg 191186, Russia

Россия, Санкт-Петербург, РГПУ им. А.И.Герцена, факультет химии, доцент кафедры органической химии

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Published

2021-10-21

Issue

Vol. 57 No. 10 (2021)

Section

Original Papers