SYNTHESIS OF METHYL 6-ARYL-5-(1H-BENZIMIDAZOL-2-YL)-2-METHYLNICOTINATES

Authors

  • И. Б. Дзвинчук Institute of Organic Chemistry National Academy of Sciences of Ukraine, Kiev 02094
  • М. О. Лозинский Institute of Organic Chemistry National Academy of Sciences of Ukraine, Kiev 02094

DOI:

https://doi.org/10.1007/6608

Keywords:

benzimidazoles, pyridines, aromatization, dearylation, Hantzsch reaction

Abstract

A three-component cyclocondensation of 4-(dimethylamino)benzaldehyde, 2-phenacyl-1H-benz-imidazoles, and methyl 3-aminobut-2-enoate in refluxing  acetic  acid occurs via a Hantzsch type reaction and is accompanied by the loss of N,N-dimethylaniline to give the previously unknown methyl 6-aryl-5-(1H-benzimidazol-2-yl)-2-methylnicotinates.

How to Cite
Dzvinchuk, I. B.; Lozinskii, M. O. Chem. Heterocycl. Compd. 2009, 45, 942. [Khim. Geterotsikl. Soedin. 2009, 1186.]

For this article in the English edition see DOI 10.1007/s10593-009-0370-z

 

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Published

2022-02-16

Issue

No. 8 (2009)

Section

Original Papers