SYNTHESIS AND PROPERTIES OF 4-CHLOROMETHYL-6-HYDROXYCOUMARINS AND 4-(2-BENZOFURYL)-6-HYDROXYCOUMARINS

Authors

  • М. С. Фрасинюк Institute of Bioorganic Chemistry and Petrochemistry, National Academy of Science of Ukraine, Kiev 02094
  • С. П. Бондаренко Taras Shevchenko Kiev National University, Kiev 01033
  • В. П. Хиля Taras Shevchenko Kiev National University, Kiev 01033

DOI:

https://doi.org/10.1007/6770

Keywords:

4-(2-benzofuryl)coumarins, 4-chloromethylcoumarins, alkylation, acylation, heterocyclization

Abstract

New 4-chloromethyl-6-hydroxycoumarins have been obtained by the condensation of hydroquinone derivatives with 4-chloroacetoacetic ester, and have  been used for the synthesis of 4-(2-benzofuryl)-6-hydroxycoumarins. Alkylation and acylation of the  phenolic hydroxyl of the synthesized 4-(2-benzo-furyl)coumarins have been investigated.

How to Cite
Frasinyuk, M. S.; Bondarenko, S. P.; Khilya, V. P.  Chem. Heterocycl. Compd. 2009, 45, 290. [Khim. Geterotsikl. Soedin. 2009, 361.]

For this article in the English edition see DOI 10.1007/s10593-009-0275-x


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Published

2022-04-26

Issue

No. 3 (2009)

Section

Original Papers