SYNTHESIS AND SOME CHEMICAL PROPERTIES OF 4-ACYL-2,6-DISILAPIPERAZINES. MOLECULAR AND CRYSTAL STRUCTURE OF 4-FORMYL-2,2,6,6-TETRAMETHYL-2,6-DISILAPIPERAZINE

Abstract

An one-pot synthesis of 4-acyl-2,6-disilapiperazines has been developed which consists of treatment of carboxamides with hexamethyldisilazane and dimethylchloromethylchlorosilane mixture with subsequent amination of the intermediate N,N-bis(dimethylchlorosilylmethyl)amides (which are derivatives of pentacoordinated silicon) with ammonia or primary amines. The hydrolytic stability of the 4-acyl-2,6-disilapiperazines and their reactions with benzenesulfonamide have been studied. The structure of 4‑formyl-2,2,6,6‑tetramethyl-2,6-disilapiperazine has been confirmed by X-ray diffraction analysis.

Authors: O. A. Zamyshlyaeva, A. G. Shipov, E. P. Kramarova, Vad. V. Negrebetsky, Yu. E. Ovchinnikov, S. A. Pogozhikh, and Yu. I Baukov.

English Translation in Chemistry of Heterocyclic Compounds, 1999, 35 (8), pp 947-953

http://link.springer.com/article/10.1007/BF02252163