α-UREIDOALKYLATION OF 1,3-BIS(HYDROXYMETHYL)IMIDAZOLIDIN-2-ONE

Authors

  • Г. А. Газиева N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow 119991
  • П. В. Ложкин N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow 119991
  • А. Н. Кравченко N. D. Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences, Moscow 119991

DOI:

https://doi.org/10.1007/7336

Keywords:

1, 3-bis(R-aminomethyl)imidazolidin-2-ones, 3-bis(hydroxymethyl)imidazolidin-2-one, 3-bis(2, 4-dioxoimidazolidin-1-yl)methylimidazolidin-2-one, α-ureidoalkylation

Abstract

The α-ureidoalkylation of imidazolidine-2,4-dione, urea, carboxylic acid amides, and sulfonamides has been studied using 1,3-bis(hydroxymethyl)-imidazolidin-2-one as ureidoalkylating agent. Methods have been developed for the synthesis of 1,3-bis(2,4-dioxoimidazolidin-1-ylmethyl)-, 1,3-bis(acetyl-aminomethyl)-, 1,3-bis(benzoylaminomethyl)-, 1,3-bis(phenylsulfonylaminomethyl)-, and  1,3-bis(p-toluenesulfonylaminomethyl)imidazolidin-2-ones.

How to Cite
Gazieva, G. A.; Lozhkin, P. V.; Kravchenko, A. N.  Chem. Heterocycl. Compd. 2007, 43, 1406. [Khim. Geterotsikl. Soedin. 2007, 1655.]

For this article in the English edition see DOI 10.1007/s10593-007-0217-4


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Published

2023-01-18

Issue

No. 11 (2007)

Section

Original Papers